Dust collector is the key component of the cleaning sweeper vehicle， so the product performance can be greatly improved by reducing the aerodynamic noise of the dust collector. Based on Fluent software and FW-H acoustic analogy model， the aerodynamic noise of dust collector was calculated. Firstly， a new kind of dust collector with shoulder structure and inclined wall was designed in this paper， and the comprehensive influence between shoulder angle and inclined angle of upper wall on the aerodynamic noise of the dust collector was mainly focused on. Based on MATLAB software， polynomial fitting was used to establish the function relations between dust collector’s total pressure and two parameters， and between total sound pressure level and two parameters， and then the objective functions were optimized by using multi-objective optimization genetic algorithm. The numerical results show that： the shoulder angle has a significant influence on aerodynamic noise， and between 0° and 20°， the noise can be reduced by 0.4dB for every one degree increase of the shoulder angle. Moreover， the aerodynamic noise of the dust collector can be reduced effectively by increasing the shoulder angle reasonably while reducing the energy loss of the dust collector， and the maximum reduction is 6.2dB.