The conical shell-folding plate structure is very common in the structure of aviation cabin, and as the bearer of major core precision scientific instruments and equipment of aviation equipment, the strength design of cabin structure is particularly critical. In this paper, the dynamic characteristics of the conical shell-folding plate structure are analyzed. Through simulation calculation, the response result of the conical shell-folding plate structure under random vibration is obtained, and the response surface function between the material parameters and the dynamic response is established. Furthermore, the Spearman rank correlation coefficient was used to analyze the sensitivity, and the main factors affecting the dynamic strength of the cabin structure in the conical shell and folded plate structure were screened out. Finally, the influence curve of each major factor on the dynamic response of the response surface is obtained.