With the development of high pressure and high power of aviation hydraulic system, the vibration problem of hydraulic pipeline is increasingly not to be ignored. Reducing the vibration of hydraulic pipeline is of great significance to improve the safety of aircraft during flight. In this paper, the vibration characteristics of aviation hydraulic pipeline under pump source pulse condition are studied, and the mathematical model of vibration characteristics of hydraulic pipeline under the influence of fluid pressure and flow rate is established. The actual hydraulic pipeline system is modeled and fluidstructure coupling simulation is carried out by using finite element software ANSYS, and the corresponding vibration response is obtained. The results show that the natural frequency of hydraulic pipeline varies with different fluid velocity and pressure. When the fluid pulsation frequency is close to the natural frequency of the pipeline system, the system will have resonance and the vibration amplitude increases greatly．