In order to improve the ride comfort of trains at high speed, the semi-active hybrid control of a train suspension was studied. A two-degree-of-freedom vehicle model was established to analyze and compare the on-off control strategy and continuous control strategy. Based on the analyses of transmission characteristics, a hybrid control strategy was proposed, and the influence of adjustment coefficient on the hybrid control strategy was studied. In order to verify the effectiveness of the control strategy, a full-vehicle model was established based on UM and Simulink. The control strategy was applied to the secondary lateral shock absorber, and the simulation analysis was carried out. The results showed that the hybrid control strategy can take into account the advantages of both on-off and continuous control strategies, the lateral acceleration of the car body is reduced and the lateral stability of the train is improved, when the adjustment coefficient is selected properly.