To overcome the limitation of traditional Reynolds equation in solving threedimensional oil film flow field, a numerical method based on six-degree-of-freedom (6DOF) model and dynamic mesh was proposed to obtain the stiffness and damping of a hybrid bearing. The hybrid bearing with typical structure was taken as an example. By developing a customization program of the 6DOF model and using the nonlinear iterative method, the transient change process of axis trajectory under an external load was calculated, and then the static equilibrium position of axle neck under the external load was obtained. By embedding the UDF macro program, a perturbation of the axle neck in the static equilibrium position was realized by the dynamic mesh updating method. The transient oil film force caused by the perturbation was calculated by solving the NavierStokes equation, and the oil film stiffness and damping of the hybrid bearing were obtained by the difference method. The variation of bearing stiffness and damping at different rotational speeds was also analyzed.