Adaptive terminal sliding mode control for spacecraft with coupled translation and attitude maneuvers is investigated in this paper. The mathematical model for the rigid spacecraft with translation and attitude coupled dynamics are obtained by means of Lagrange′s equations in terms of general quasi?coordinates. An adaptive fast terminal sliding mode control is proposed for spacecraft to achieve translation and attitude maneuvers in the presence of model uncertainties and environmental perturbations. This adaptive procedure consists of the estimation of the uncertainty and disturbance and ensures the effective suppression of the undesired chattering. The reach?ability and the stability of the controllers are proved by means of the Lyapunov′s stability theory. The efficiency and the accuracy of the proposed controller are examined through numerical simulations of the spacecraft position and attitude tracking maneuvers.