The active vibration control of a cantilevered laminated plate is investigated in this paper by using velocity feedback control method, where multiple macro fiber composite (MFC) and PVDF patches are bonded on the top and bottom surfaces of the plate to act as the actuators and sensors, respectively. By using Hamilton’s principle and the assumed mode method, the dynamical model of the structural systems is developed with considering the effects of mass and stiffness of MFC actuators. In order to obtain the maximum control forces or moments, the MFC actuators and PVDF sensors are placed in the regions with high average strain of host structure. Frequency and time domain responses of the cantilevered plate are obtained. And the required control voltages of MFC actuators are also calculated. Moreover, the placements of MFC actuators are presented for cantilevered laminated plate with different fiber orientation angle.