To overcome the passive effect of disturbance and actuator failures for control systems, and make systems anti-jamming and fault-tolerant, the problem of robust H∞ reliable control for uncertain nonlinear systems under arbitrary switching law is investigated. It is assumed that all of systems matrices contain parameter uncertainties and the systems contain external unknown nonlinear disturbance. When some actuators experience failures, LMI(linear matrix inequality) technique and common Laypunov function method are adopted to design robust suboptimal H∞ reliable controller to guarantee the systems globally quadratically stability and H∞ performance for all arbitrary switching law. Finally, robust optimal H∞ reliable controller is obtained by solving a convex optimization problem. Simulation results illustrate that the feasibility and validity of the reliable controller under arbitrary switching law.