Based on the neural morphology and multicompartment model, this paper constructed the corresponding compartment models of cerebellar cortex purkinje neuron, olfactory bulb mitral neuron and hippocampus CA1 pyramidal neuron. By analyzing the action potential, the different action potentials of the three neural circuit’s principal neurons under different types of external stimuli were illustrated. For the same type of external stimuli , the action potential of the three different neural circuit’s principal neurons were also illustrated. The model results verify that the three different neural circuits have different output functions in their nervous system.