Concerning the waverider generated by the constant wedge angle method, this paper obtained its lift-drag ratios through the external viscous fields directly calculated by CFD. Then the genetic algorithm, with the maximum lift-drag ratio as the goal,was applied to obtain a group of optimized parameters of the waverider configurations. The real meshes and whole calculations were obtained by the command line interface of Gambit and Fluent. Matlab and Bash script programming were introduced to automate the whole optimization procedure. Finally, based on the optimized configurations,the lift coefficients, drag coefficients and lift-drag ratios were calculated with hundreds of in-flow Mach numbers and angle of attacks.Some interesting phenomena occured and were depicted.