The theoretical analysis,modeling and numerical simulation of the KKV's hypervelocity impact damage to typical target were presented by means of basic conservation law of mass,momentum and energy, and software ANSYS/LS- DYNA. The KKV's impact damage effect to ballistic missile in condition of different attack angle and different distance of eccentric were analyzed, and the feasibility of the method were proven by simulation test.The result indicates that the KKV's impact damage database could be explored based on full-size modeling and simulation by using high-speed computer.